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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BECN1
All Species:
10.61
Human Site:
S104
Identified Species:
15.56
UniProt:
Q14457
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14457
NP_003757.1
450
51896
S104
F
T
L
I
G
E
A
S
D
G
G
T
M
E
N
Chimpanzee
Pan troglodytes
XP_511522
450
51866
S104
F
T
L
I
G
E
A
S
D
G
G
T
M
E
N
Rhesus Macaque
Macaca mulatta
XP_001111932
450
51890
S104
F
T
L
I
G
E
A
S
D
G
G
T
M
E
N
Dog
Lupus familis
XP_537634
362
42279
R76
R
F
I
P
P
A
R
R
C
L
E
I
L
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
O88597
448
51515
C138
D
H
P
L
C
E
E
C
T
D
T
L
L
D
Q
Rat
Rattus norvegicus
Q91XJ1
448
51538
C138
D
H
P
L
C
E
E
C
T
D
T
L
L
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514527
394
45783
N105
I
T
E
N
E
C
Q
N
Y
K
R
C
L
E
I
Chicken
Gallus gallus
Q5ZKS6
447
51416
N108
S
D
G
G
T
M
E
N
L
S
R
R
L
K
V
Frog
Xenopus laevis
Q6GP52
445
51275
C135
D
H
P
L
C
E
E
C
T
D
T
L
L
D
Q
Zebra Danio
Brachydanio rerio
P13104
284
32704
Tiger Blowfish
Takifugu rubipres
NP_001032963
447
51199
H108
S
D
C
G
N
M
E
H
L
S
R
R
L
K
V
Fruit Fly
Dros. melanogaster
Q9VCE1
422
48852
C112
S
E
I
D
H
P
L
C
E
E
C
A
D
S
M
Honey Bee
Apis mellifera
XP_392365
430
49618
D107
L
S
S
S
S
S
A
D
H
P
L
C
D
E
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786368
415
47747
T108
H
P
L
C
E
E
C
T
D
S
L
L
D
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M367
517
58486
P139
L
E
V
G
Q
N
G
P
L
H
S
N
T
S
G
Baker's Yeast
Sacchar. cerevisiae
Q02948
557
63242
Q149
T
D
E
D
E
N
Q
Q
I
Q
L
N
S
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
78.8
N.A.
97.3
97.3
N.A.
76.8
91.7
88.6
20
81.1
49.1
56.4
N.A.
57.5
Protein Similarity:
100
99.7
99.7
79.5
N.A.
98
98.2
N.A.
81.5
94.6
94.8
36.4
89.5
67.7
69.3
N.A.
71.5
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
13.3
0
6.6
0
0
0
13.3
N.A.
20
P-Site Similarity:
100
100
100
20
N.A.
26.6
26.6
N.A.
26.6
20
26.6
0
13.3
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
25
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
7
7
19
7
7
25
7
0
7
13
0
0
7
% C
% Asp:
19
19
0
13
0
0
0
7
25
19
0
0
19
19
0
% D
% Glu:
0
13
13
0
19
44
32
0
7
7
7
0
0
38
0
% E
% Phe:
19
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
19
19
0
7
0
0
19
19
0
0
0
7
% G
% His:
7
19
0
0
7
0
0
7
7
7
0
0
0
0
0
% H
% Ile:
7
0
13
19
0
0
0
0
7
0
0
7
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
0
0
0
19
0
% K
% Leu:
13
0
25
19
0
0
7
0
19
7
19
25
44
0
7
% L
% Met:
0
0
0
0
0
13
0
0
0
0
0
0
19
0
7
% M
% Asn:
0
0
0
7
7
13
0
13
0
0
0
13
0
0
19
% N
% Pro:
0
7
19
7
7
7
0
7
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
13
7
0
7
0
0
0
7
25
% Q
% Arg:
7
0
0
0
0
0
7
7
0
0
19
13
0
0
0
% R
% Ser:
19
7
7
7
7
7
0
19
0
19
7
0
7
13
0
% S
% Thr:
7
25
0
0
7
0
0
7
19
0
19
19
7
0
7
% T
% Val:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _